What is the therapeutic serum level range for lithium?

What is the therapeutic serum level range for lithium?

• A. 0.4-0.8
• B. 0.6-1.2
• C. 1.3-1.9
• D. 2.0-2.5

Answer: (B)

Lithium has a narrow therapeutic index, so the target serum level for maintenance is 0.6 to 1.2 mEq/L. This range balances mood stabilization with a lower risk of toxicity. Levels below 0.6 are typically subtherapeutic and may not control symptoms, while levels above 1.2 increase the chance of toxicity, which can present with tremors, GI upset, confusion, and ataxia. Regular monitoring is essential, along with maintaining consistent hydration and salt intake, and watching for drug interactions that can raise lithium levels.

Lithium has a narrow therapeutic index, so the target serum level for maintenance is 0.6 to 1.2 mEq/L. This range balances mood stabilization with a lower risk of toxicity. Levels below 0.6 are typically subtherapeutic and may not control symptoms, while levels above 1.2 increase the chance of toxicity, which can present with tremors, GI upset, confusion, and ataxia. Regular monitoring is essential, along with maintaining consistent hydration and salt intake, and watching for drug interactions that can raise lithium levels.